Principal Investigator
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Positions Held
Current positions
- 2021~ Adjunct Associate Professor, Biomedical Industry Ph.D. Program
- 2020~ Associate Professor, Institute of Clinical Medicine, National Yang Ming Chiao Tung University
- 2020~ Adjunct Associate Professor, Institute of Emergency and critical care medicine, National Yang Ming Chiao Tung University
- 2017~ Adjunct Associate Professor, Taiwan International Graduate Program- Molecular Medicine program,
Academia Sinica- National Yang-Ming University Joint Curriculum
- 2015/8 ~ 2020/1 Assistant Professor, Institute of Clinical Medicine, National Yang-Ming University Taiwan
- 2014/9 ~ 2016/8 Visiting position with a title of Assistant Professor Scholar, Genomic Research Center, Academia Sinica, Taiwan
- 2014/8 ~ 2015/7 Assistant Professor, College of Medicine, Department of Microbiology and Immunology, Taipei Medical University
- 2012/7 ~ 2014/7 Post-doctoral fellow, Lineberger Comprehensive Cancer center, University of North Carolina at Chapel Hill, USA
- 2009/1 ~ 2012/6 Post-doctoral fellow, Genomic Research Center, Academia Sinica, Taiwan
- 2009/1 Ph.D., Graduate Institute of Microbiology and Immunology, College of Life Science, National Yang-Ming University
- 2000/7 ~ 2003/7 Scientist, Anawratha biotechnology Inc.
Awards and honors
Research-related
Others
- 2023, Wu Ho-Su TBF Taiwan Bio-development Foundation Medical Award
- 2023, Travel Grant Winner, 15TH International Congress on Systemic Lupus Erythematosus
- 2020, College Student Research Creativity Award, Ministry of Science and Technology
(指導學生獲得109學年度科技部大專生研究計畫研究創作獎, 2020) - 2019, Outstanding Research Scholar Award, Chinese Society of Immunology
- 2017, Project for Excellent Junior Research Investigators, Ministry of Science and Technology
(科技部優秀年輕學者研究計畫, 2017-2020) - 2012, Award of Postdoctoral Research Abroad Program-2 years, “National Science Council”, TW
(國科會補助赴國外從事博士後研究,千里馬計畫兩年期) - 2009, Award of Long –Term Smile Contest, “Acer Foundation”, TW
- 2009, Outstanding Thesis award, “Chien-Tien Hsu Foundation” in the Chinese society of cell and molecular biology, TW
- 2009, Distinguished Thesis award, “Tiente Lee Biomedical Foundation”, TW
- 2009, Outstanding Thesis award, Yang-Ming University, TW
- 2006, Zong-Ren Chen Immunology of Research & Development Foundation, TW
Others
- 2022, Excellent Teaching Award, College of Medicine, National Yang Ming Chiao Tung University
(國立陽明交通大學醫學院院級教學傑出獎) - 2020, Excellent Teaching Award, National Yang-Ming University School of Medicine
(國立陽明大學醫學院院級教學傑出獎) - 2017, Excellent Teacher Award, Institute of Clinical Medicine, National Yang-Ming University
(國立陽明大學臨床醫學研究所教學傑出教師)
學生得獎紀錄
- 2024年度,第38屆生物醫學聯合學術年會,第三屆永信李天德醫藥基金會壁報論文比賽,特優。得獎人:陳家華
- 2023年度,第19屆永信李天德醫藥科技獎,傑出論文獎,得獎人:曹彥博
- 2023年度,中華免疫學學會,莊淑綺女士SLE研究獎,得獎人:曹彥博
- 2023年度,第19屆榮台聯大研究成果發表會壁報獎,臨床醫學組I第二名,得獎人:柯宏儒,陳怡君,莊雯婷
- 2022年度,中華民國風濕病醫學會,第四十屆學術論文研討會優秀論文 第二名及第三名,得獎人:曹彥博
- 2022年度,第36屆生物醫學聯合學術年會,第一屆永信李天德醫藥基金會壁報論文獎,得獎人:陳家華
- 2022年度,全國臨床醫學研究所聯合教學,第十二屆臨床醫學研究所聯合教學研究研討會海報競賽第二名,得獎人:柯宏儒
- 2022年度,國立陽明交通大學,110學年度學術論文研討會臨床醫學與公共衛生研究組_優等,得獎人:柯宏儒
- 2021年度,福爾摩沙春季免疫學校(Formosa Immunology Spring School),中華民國免疫學會 Travel Award,得獎人: 趙之偉
- 2021年度,中華民國免疫學年會年度大會,口頭論文發表 優勝,得獎人:曹彥博
- 2020年度,科技部,大專生研究計畫研究創作獎,得獎人:陳品妤
- 2020年度,中華民國免疫學會,會員大會暨學術研討會 海報論文發表優勝,得獎人:Babamale (巴巴馬)
文獻發表
- Kang H-R, Han J-H, Ng Y-C, Ryu Seungbo, Park J-Y, Chung W-C, Song Y-J, Chen S-T, Brickey W-June, Ting P-T Jenny, Song M-J Dynamic bidirectional regulation of NLRC3 and gammaherpesviruses during viral latency in B lymphocytes. J Med Virol 2024 Mar;96(3)...(PubMed)
- Chen P-Y, Yen J-C, Liu T-T, Chen S-T, Wang S-J, Chen S-P. Neuronal NLRP3 inflammasome mediates spreading depolarization-evoked trigeminovascular activation. Brain Ju3;146(7):2989-3002 (20)...(PubMed)
- Tsao Y-P Tseng F-Y, Chao C-W, Chen M-H, Yeh Y-C, Abdulkareem B-O, Chen S-Y, Chuang W-T, Chang P-C, Chen I-C, Wang P-H, Wu C-S, Tsai C-Y, and Chen S-T*. NLRP12 is an innate immune checkpoint for repressing IFN signatures and attenuating lupus nephritis progression. Journal of Clinical Investigation Feb 1;133(3):e157272 (2023) *corresponding author...(PubMed)
- Chou J-M, Tsai J-L, Hung J-N, Chen I-Hua, Chen S-T, Tsai M-H The ORF8 protein of SARS-CoV-2 modulates the spike protein and its implications in viral transmission. Frontiers in Microbiology May 19;13:883597 (2022)...(PubMed)
- Abdulkareem Olarewaju Babamale and Chen S-T*, Nod-Like Receptors: Critical Intracellular Sensors for Host Protection and Cell Death in Microbial and Parasitic Infections. Int. J. Mol. Sci. Oct 22;22 (21):11398 (2021) *corresponding author...(PubMed)
- Chou Y-J, Lin C-C, Chen N-J, Lin, C-H, Lin C-C, Chen S-T, Chen K-H & Fu S-L. Vaccine adjuvant activity of a TLR4-activating synthetic glycolipid by promoting autophagy. Scientific Reports May 21;10(1):8422 (2020)...(PubMed)
- Chen, S-Y, Chen, S-T, Lin, J-Y, Lin, C-Y. Reconstitution of Injectable Poly-d,l-lactic Acid: Efficacy of Different Diluents and a New Accelerating Method. Plastic and Reconstructive Surgery 8(5): e2829 (2020)...(PubMed)
- Yang W-S, Lin T-Y, Chang-L, Yeh W, Huang S-C, Chen T-Yi, Hsieh Y-T, Chen Sz-T, Li W-C, Pan C-C, Yen C-H, l Chang P-C. HIV-1 Tat Interacts with a Kaposi’s Sarcoma-Associated Herpesvirus Reactivation-Upregulated Antiangiogenic Long Noncoding RNA, LINC00313, and Antagonizes Its Function. Journal of virology 17; 94(3): e01280-19 (2020)....(PubMed)
- Chen S-T*, Chen L, Lin S-C., Chen, S-Y., Tsao Y-P., Guo-H., Li-F-J., Tseng W-T., Tam-Jason., Chao C-W., Ting P.J.*, NLRP12 Regulates Anti-viral RIG-I Activation via Interaction with TRIM25. Cell Host& Microbe 25, 1-15 (2019) *corresponding author....(PubMed)
- Chen S-T, Li, F-J, Hsu, T-Y, Liang, S-M, Yeh, -Y-C, Liao, W-Y, Chou, T-Y, Chen, N-J and Hsieh, S-L, CLEC5A is a critical receptor in innate immunity against Listeria infection. Nature Communications, 8 Article number:299 (2017)....(PubMed)
- Teng O, Chen S-T, Hsu T-L, Sia S-F, Cole S, Valkenburg SA, Hsu TY, Zheng JT, Tu W, Bruzzone R, Peiris JS, Hsieh SL, Yen HL. CLEC5A-Mediated Enhancement of the Inflammatory Response in Myeloid Cells Contributes to Influenza Virus Pathogenicity In Vivo. Journal of Virology Jan. Vol. 91 no. 1 e01813-16 (2017)...(PubMed)
- Liang C-C, Chen S-Y Chen, T-Y and Chen S-T, Central Nervous System Melioidosis Mimics Malignancy: A Case Report and Literature World Neurosurg. May; 89:732.e19-23 (2016)...(PubMed)
- Huang, Y-L, Chen, S-T¶, Liu, R-S, Chen, Y-H, Shu, P-Y, and Hsieh, S-L, CLEC5A is critical for dengue virus-induced osteoclast activation and bone homeostasis. Journal of Molecular Medicine Sep; 94 (9) 1025-37 (2016) ¶ Equal contribution....(PubMed)
- Huang M-T, Chen, S-T, Wu, H-Y, Chen, Y-J, Chou, T-Y, and Hsieh, S-L,DcR3 suppresses influenza virus-induced macrophage activation and attenuates pulmonary inflammation and lethality. Journal of Molecular Medicine Oct;93(10):1131-43 (2015)...(PubMed)
- Wu, M-F, Chen, S-Tand Hsieh, S-L, Distinct regulation of dengue virus-induced inflammasome activation in human macrophage subsets. Journal of Biomedical Science 20:36 (2013)...(PubMed)
- Wu, M-F, Chen, S-T, Yang, A.H., Lin, W.W., Lin, Y.L.and Hsieh, S.L., CLEC5A is critical for dengue-virus induced Inflammasome activation in human macrophages. Blood 121, 95-106 (2013)....(PubMed)
- Chen, S-T, Liu R-S, Wu M-F, Lin Y-L, Chen S-Y, Tan D-W, Chou T-Y, Tsai, I-S, Li-L, Hsieh S-L CLEC5A Regulates Japanese Encephalitis Virus-Induced Neuroinflammation and Lethality. PLoS Pathogens, 8(4): e1002655 (2012)....(PubMed)
- Chen S-T, Lin Y-L, Huang M-T, Wu M-F, Hsieh S-L, Targeting C-type lectin for the treatment of flavivirus infections. Adv Exp Med Biol. 705, 769-776 (2011)....(PubMed)
- Chen, S-T, Lin, Y-L, Huang, M-T, Wu, M-F, Cheng, S-C, Lei, H-Y, Lee, C-K, Chiou, T-W, Wong, C-H, and Hsieh, S-L, CLEC5A is critical for dengue virus-induced lethal disease. Nature 453, 672-676 (2008)...(PubMed)